Material-specific properties applied to an environmental risk assessment of engineered nanomaterials – implications on grouping and read-across concepts
| Autor: | Henning Wigger, Bernd Nowack |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Computer science
Pooling Engineered nanomaterials Biomedical Engineering Fresh Water 02 engineering and technology 010501 environmental sciences Toxicology Ecotoxicology 01 natural sciences Risk Assessment Environmental risk Aluminum Oxide Predicted no-effect concentration 0105 earth and related environmental sciences Environmental risk assessment Titanium Nanotubes Carbon Environmental exposure Environmental Exposure 021001 nanoscience & nanotechnology Hazard Nanostructures Environmental Pollutants Biochemical engineering 0210 nano-technology Risk assessment |
| Zdroj: | Nanotoxicology |
| DOI: | 10.6084/m9.figshare.9517685.v1 |
| Popis: | Engineered nanomaterials (ENMs) are intentionally designed in different nano-forms of the same parent material in order to meet application requirements. Different grouping and read-across concepts are proposed to streamline risk assessments by pooling nano-forms in one category. Environmental grouping concepts still are in their infancy and mainly focus on grouping by hazard categories. Complete risk assessments require data on environmental release and exposure not only for ENMs but also for their nano-forms. The key requirement is to identify and to distinguish the production volumes of the ENMs regarding nano-form-specific applications. The aim of our work was to evaluate whether such a grouping is possible with the available data and which influence it has on the environmental risk assessment of ENMs. A functionality-driven approach was applied to match the material-specific property (i.e. crystal form/morphology) with the functions employed in the applications. We demonstrate that for nano-TiO2, carbon nanotubes (CNTs), and nano-Al2O3 the total production volume can be allocated to specific nano-forms based on their functionalities. The differentiated assessments result in a variation of the predicted environmental concentrations for anatase vs. rutile nano-TiO2, single-wall vs. multi-wall CNTs and α- vs. γ-nano-Al2O3 by a factor of 2 to 13. Additionally, the nano-form-specific predicted no-effect concentrations for these ENMs were derived. The risk quotients for all nano-forms indicated no immediate risk in freshwaters. Our results suggest that grouping and read-across concepts should include both a nano-form release potential for estimating the environmental exposure and separately consider the nano-forms in environmental risk assessments. |
| Databáze: | OpenAIRE |
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