Effect of transforaminal epidural polydeoxyribonucleotide injections on lumbosacral radiculopathy: A case report
| Autor: | Keum Nae Kang, Han Byeol Oh, Jin Woo Koh, Young Uk Kim, Tae Woong Kim, Mi Sook Seo, Jong-Uk Mun |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Sacrum Injections Epidural Disc protrusion 03 medical and health sciences 0302 clinical medicine Polydeoxyribonucleotides 030202 anesthesiology medicine Humans case report Clinical Case Report Radiculopathy Lumbar Vertebrae glucocorticoids business.industry Anti-Inflammatory Agents Non-Steroidal lumbosacral radiculopathy Type 2 Diabetes Mellitus General Medicine transforaminal epidural block medicine.disease Low back pain Surgery Metformin Glimepiride Pain Clinics diabetes mellitus Lumbosacral radiculopathy medicine.symptom polydeoxyribonucleotide business Low Back Pain 030217 neurology & neurosurgery Glucocorticoid Intervertebral Disc Displacement medicine.drug Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Rationale: Transforaminal epidural glucocorticoids administration is widely performed for the management of lumbosacral radiculopathy. However, it may worsen the condition of patients with type 2 diabetes mellitus (DM). Polydeoxyribonucleotide (PDRN) was recently noted as a substitute for glucocorticoids. Patient concerns: A 44-year-old male patient was admitted to our pain clinic with symptoms of low back pain with severe pain and tingling sensation of left posterolateral leg. He had type 2 DM medicated with Glimepiride and Metformin. Blood glucose level was 367 mg/dL. He declined to use glucocorticoid. Diagnoses: He was diagnosed as left foraminal disc protrusion at L4–5, left subarticular disc protrusion at L5-S1. Interventions: Fluoroscopically guided transforaminal epidural PDRN injections were carried out. Outcomes: The patient was followed up for more than 6 months and demonstrated good improvement in lumbosacral radiculopathy without any complications. Lessons: This is the first successful report on epidural injection of PDRN. |
| Databáze: | OpenAIRE |
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