The burden of atherosclerosis in Portugal
| Autor: | Francisco Lourenço, Alberto Mello e Silva, João Costa, Margarida Borges, Daniel Caldeira, R. Ascenção, J. Alarcão, Miguel Gouveia, Francisco Araújo, Víctor Gil, F Fiorentino, Filipa Sampaio, António Vaz Carneiro |
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| Přispěvatelé: | Veritati - Repositório Institucional da Universidade Católica Portuguesa, Repositório da Universidade de Lisboa |
| Rok vydání: | 2020 |
| Předmět: |
Burden of disease
Aterosclerose Reproduction (economics) Library science Signs and symptoms DALYs Custo da Doença Life Expectancy Cost of Illness Cost of illness Medicine Humans Cardiac and Cardiovascular Systems AcademicSubjects/MED00200 Mortality License Kardiologi Portugal business.industry Health Policy Disability-Adjusted Life Years Public Health Global Health Social Medicine and Epidemiology Creative commons Original Articles Atherosclerosis language.human_language Folkhälsovetenskap global hälsa socialmedicin och epidemiologi Premature death language Quality-Adjusted Life Years Portuguese Morbidity Cardiology and Cardiovascular Medicine business |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP European Heart Journal. Quality of Care & Clinical Outcomes |
| ISSN: | 2058-1742 |
| Popis: | © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contactjournals.permissions@oup.com Aims: This paper sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016. Methods and results: The burden of atherosclerosis was measured in disability-adjusted life years (DALY) following the latest 2010 Global Burden of Disease (GBD) methodology. DALYs were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clinical manifestations of atherosclerosis were included: ischemic heart disease (IHD) (including acute myocardial infarction (AMI), stable angina, and ischemic heart failure (IHF)), ischemic cerebrovascular disease (ICVD) and peripheral arterial disease (PAD). YLL were estimated based on all-cause mortality data for the Portuguese population and mortality due to IHD, ICVD and PAD for the year 2016 sourced from national statistics. Standard life expectancy was sourced from the GBD study. YLD corresponded to the product of the number of prevalent cases by an average disability weight (DW) for all possible combinations of disease. Prevalence data for the different clinical manifestations of atherosclerosis were sourced from epidemiological studies. DW were sourced from the published literature. In 2016, 15,123 deaths were attributable to atherosclerosis, which corresponded to 14.3% of overall mortality in mainland Portugal. DALYs totaled 260,943, 75% due to premature death (196,438 YLL) and 25% due to disability (64,505 YLD). Conclusion: Atherosclerosis entails a high disease burden to society. A large part of this burden would be avoidable if evidence-based effective and cost-effective interventions targeting known risk factors, from prevention to treatment, were implemented. This study was funded by Bayer Portugal, Lda. Funding was independent of the study outcomes. |
| Databáze: | OpenAIRE |
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