Leg ulceration due to cutaneous melioidosis in a returning traveller
| Autor: | Stephen Morris-Jones, Christiana Stavrou, Ophelia Veraitch, Stephen L. Walker |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Burkholderia pseudomallei Melioidosis Burkholderia medicine.drug_class Antibiotics tropical medicine (infectious disease) Ceftazidime Case Report 030105 genetics & heredity 03 medical and health sciences Wound care 0302 clinical medicine medicine Humans infections Asia Southeastern Ulcer Leg medicine.diagnostic_test Burkholderia thailandensis biology business.industry Australia General Medicine Thailand biology.organism_classification medicine.disease Dermatology dermatology Clinical microbiology Northern australia Skin biopsy business 030217 neurology & neurosurgery wound care medicine.drug |
| Zdroj: | BMJ Case Reports |
| ISSN: | 1757-790X |
| Popis: | A 26-year-old man, returned to the UK having travelled extensively in Asia. He was referred with a 3-month history of distal leg ulceration following an insect bite while in Thailand. Despite multiple courses of oral antibiotics, he developed two adjacent ulcers. A wound swab isolated an organism identified as Burkholderia thailandensis. The histology of the skin biopsy was non-specific. A diagnosis of cutaneous melioidosis was made, based on clinical and microbiological grounds. The ulcers re-epithelialised on completion of intravenous ceftazidime followed by 3 months of high dose co-trimoxazole and wound care. Many clinical microbiology laboratories have limited diagnostics for security-related organisms, with the result that B. pseudomallei, the causative bacterium of melioidosis, may be misidentified. This case highlights the importance of maintaining high levels of clinical suspicion and close microbiological liaison in individuals returning from South-East Asia and northern Australia with such symptoms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|