Can impairment in memory, language and executive functions predict neuropsychiatric symptoms in Alzheimer's disease (AD)? Findings from a cross-sectional study
| Autor: | Salvador González-Barón, Miguel Ángel Barbancho, Marcelo L. Berthier, Cristina Green, J.P. Lara, Belén Cruz, José María García-Alberca |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Aging medicine.medical_specialty Health (social science) Cross-sectional study Neuropsychological Tests Executive Function Fluency Alzheimer Disease Prevalence medicine Humans Dementia Psychiatry Aged Aged 80 and over Language Disorders Memory Disorders Mini–Mental State Examination medicine.diagnostic_test Cognition Middle Aged medicine.disease Executive functions Test (assessment) Cognitive test Cross-Sectional Studies Female Geriatrics and Gerontology Cognition Disorders Psychology Gerontology Clinical psychology |
| Zdroj: | Archives of Gerontology and Geriatrics. 52:264-269 |
| ISSN: | 0167-4943 |
| DOI: | 10.1016/j.archger.2010.05.004 |
| Popis: | The authors performed a cross-sectional study to examine the relationship between specific cognitive domains and behavioral and psychological symptoms in dementia (BPSD) in 125 patients with probable AD. Cognitive deficits were evaluated with the mini mental state examination (MMSE), trail-making test (TMT), Rey auditory verbal learning test (RAVLT), and semantic fluency test (SFT) and phonemic fluency test (PhFT), whereas the neuropsychiatric inventory (NPI) was used to rate BPSD. Patients’ performance in cognitive tests significantly correlated with total NPI scores (p < 0.0001). After controlling for demographic and clinical characteristics, cognitive impairments in memory, executive function, and language (RAVLT, TMT, PhFT, SFT) importantly estimated total NPI scores (p < 0.001, multivariate regression models). These findings suggest that the evaluation of cognitive domains may have a predictive value for the occurrence of BPSD. |
| Databáze: | OpenAIRE |
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