Análise da intolerância à lactose em alunos com sintomas sugestivos da síndrome do intestino irritável
| Autor: | Bruna Pessoa Nóbrega, Ingrid Dantas Sampaio Leite, José Weberton Rodrigues, Samara Pereira de Almeida, Jarbas Delmoutiez Ramalho Sampaio Filho, Cleise de Jesus Silva |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Abdominal pain Constipation Adolescent Testes respiratórios Síndrome do intestino irritável Hidrogênio análise Gastroenterology Hydrogen analysis Irritable Bowel Syndrome Young Adult Lactose Intolerance Internal medicine Breath tests medicine Humans Intolerância à lactose lcsh:RC799-869 Students Irritable bowel syndrome Breath test Lactose intolerance medicine.diagnostic_test business.industry Dor abdominal Middle Aged medicine.disease Diarrhea Breath Tests Quality of Life lcsh:Diseases of the digestive system. Gastroenterology Female medicine.symptom business Flatulence Hydrogen breath test |
| Zdroj: | Arquivos de Gastroenterologia, Vol 56, Iss 3, Pp 304-311 Arquivos de Gastroenterologia v.56 n.3 2019 Arquivos de gastroenterologia Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia instacron:IBEPEGE Arquivos de Gastroenterologia, Volume: 56, Issue: 3, Pages: 304-311, Published: 30 SEP 2019 |
| ISSN: | 1678-4219 |
| Popis: | BACKGROUND: Irritable bowel syndrome is a clinical condition presenting pain, distension and abdominal fullness, diarrhea, constipation, and other symptoms. It generates significant impacts on the quality of life of those affected. The pathophysiology is uncertain, but the role of various food types has been established in bowel sensitivity and its clinical manifestations. Carbohydrate intolerance, particularly to lactose, generates similar and sometimes indistinguishable symptoms from irritable bowel syndrome, and in clinical practice is both a frequent and underdiagnosed condition. Carbohydrate intolerance is related to enzymatic deficiencies, alterations of intestinal microbiota and even genetic change. The principal test for a diagnosis of lactose intolerance is the breath test, which measures hydrogen emission (produced only by bacteria), after ingestion of the corresponding substrate. OBJECTIVE: The present work aims to verify the prevalence of lactose intolerance in university students, presenting gastrointestinal symptoms suggestive of irritable bowel syndrome. METHODS: In a transversal study, to screen for those with suggestive symptoms, 124 medicine students participated by responding to a form. Those with abdominal pain were referred for anti-parasite treatment in order to exclude intestinal parasites as a secondary cause. Subsequently, using the hydrogen breath test, bacterial overgrowth was investigated, and if negative, lactose intolerance testing would be performed. Patients presenting high hydrogen concentrations of ≥20 ppm above the basal level were considered lactose intolerant. RESULTS: Of the total of students researched (n=124), 7 were excluded because they did not completing all study phases. From those 117 individuals effectively included in the survey; 8 (6.8%) were diagnosed with lactose intolerance and 2 (1.7%) with bacterial overgrowth. Intolerance was more frequent in; female individuals (75%), age range 18 to 25 years (62.5%), being colored (50%), and in their 5th semester of studies (37.5%). The presence of at least one gastrointestinal symptom among those presenting intolerance (100%), and those not presenting intolerance (42.2%) was found (P=0.002). In addition to abdominal pain (100%) (P |
| Databáze: | OpenAIRE |
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