Benzopyran derivatives from endophytic Daldinia eschscholzii JC-15 in Dendrobium chrysotoxum and their bioactivities
| Autor: | Bao-Hui Ruan, Zhong-Tao Ding, Hao Zhou, Ya-Bin Yang, Qing-Yan Zhou, Shu-Quan Li, Bang-Yan Wang, Zhuo-Xi Zhang, Ming Hu, Xue-Qiong Yang |
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| Rok vydání: | 2017 |
| Předmět: |
Natural product
Traditional medicine biology 010405 organic chemistry Daldinia eschscholzii Glucose uptake Organic Chemistry Plant Science biology.organism_classification Antimicrobial 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry Nitric oxide Benzopyran 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Dendrobium chrysotoxum |
| Zdroj: | Natural Product Research. 33:1431-1435 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2017.1419236 |
| Popis: | Five new benzopyran derivatives (2–6) and a new natural product (1) were isolated from endophytic Daldinia eschscholzii in Dendrobium chrysotoxum and determined as (R)-2,3-dihydro-2,5-dihydroxy-2-methylchromen-4-one (1), (2R, 4S)-2,3-dihydro-2-methyl-benzopyran-4,5-diol (2), (R)-3-methoxyl-1-(2,6-dihydroxy phenyl)-butan-1-one (3), 7-O-α-d-ribosyl-5-hydroxy-2-methyl-4H-chromen-4-one (4), 7-O-α-d-ribosyl-2,3-dihydro-5-hydroxy-2-methyl-chromen-4-one (5), daldinium A (6). These compounds were evaluated for their antimicrobial activity, anti-acetylcholinesterase, nitric oxide inhibition, anticoagulant, photodynamic antimicrobial activities and glucose uptake of adipocytes. Some compounds showed photoactive antimicrobial activities and glucose uptake stimulating activities. |
| Databáze: | OpenAIRE |
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