Oral amelanotic malignant melanoma: a case report
| Autor: | Mohamed Chehbouni, Salma Aboulouidad, Nadia Mansouri Hattab, Abdelaziz Raji, Zakaria Aziz, Mohamed El Bouihi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
030231 tropical medicine Tumor resection Metastasis 03 medical and health sciences 0302 clinical medicine Medicine case report 030212 general & internal medicine Amelanotic melanoma Malignant melanoma amelanotic oral cavity maxillary gingiva business.industry Melanoma Treatment delay General Medicine medicine.disease medicine.anatomical_structure Immunohistochemistry Hard palate Radiology business Wide resection |
| Zdroj: | Pan African Medical Journal; Vol. 37 No. 1 (2020) The Pan African Medical Journal |
| ISSN: | 1937-8688 |
| Popis: | Amelanotic malignant melanoma is an extremely rare and aggressive oral tumor. Herein we report the case of a 42-year-old woman presented with a painful growth in anterior maxillary region. Intra-oral examination showed a non-pigmented exophytic mass occupying the anterior maxillary sector. Incisional biopsy with immunohistochemistry examination revealed a malignant melanoma as it strongly expressed melan A and S-100. Facial computed tomography showed extension to the maxillary bone and hard palate. After thoraco-abdominal computed tomography revealing absence of metastasis, tumor resection was performed respecting 2cm security margin. Oral localization of malignant melanoma is rare especially its amelanotic variant. Lack of pigmentation makes the diagnosis more difficult, usually resulting in treatment delay and making the prognosis even worse. Early detection by histological and immunochemistry examination combined to wide resection are the keys to improving the survival for patients with oral amelanotic melanoma. |
| Databáze: | OpenAIRE |
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