Design of a force-measuring setup for colorectal compression anastomosis and first ex-vivo results
| Autor: | Dirk Wilhelm, Petra Mela, Maximilian Berlet, Stefanie Ficht, Jana Steger, Markus Eblenkamp, Isabella Patzke |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Materials science
Colon Anastomosis Swine 0206 medical engineering Tissue thickness Biomedical Engineering Lumen (anatomy) Health Informatics 02 engineering and technology 01 natural sciences Forces 010309 optics Body piercing 0103 physical sciences Pressure Animals Radiology Nuclear Medicine and imaging Implants Dimensioning Digestive System Surgical Procedures interests Piercing Anastomosis Surgical Rectum Endoscopy General Medicine Colonoscopy Neoplasms Experimental Compression (physics) 020601 biomedical engineering Computer Graphics and Computer-Aided Design ddc Computer Science Applications Biomechanical Phenomena Surgery Original Article Computer Vision and Pattern Recognition Implant Colorectal Neoplasms interests.hobby Ex vivo Biomedical engineering |
| Zdroj: | International Journal of Computer Assisted Radiology and Surgery |
| ISSN: | 1861-6429 1861-6410 |
| Popis: | Purpose The introduction of novel endoscopic instruments is essential to reduce trauma in visceral surgery. However, endoscopic device development is hampered by challenges in respecting the dimensional restrictions, due to the narrow access route, and by achieving adequate force transmission. As the overall goal of our research is the development of a patient adaptable, endoscopic anastomosis manipulator, biomechanical and size-related characterization of gastrointestinal organs are needed to determine technical requirements and thresholds to define functional design and load-compatible dimensioning of devices. Methods We built an experimental setup to measure colon tissue compression piercing forces. We tested 54 parameter sets, including variations of three tissue fixation configurations, three piercing body configurations (four, eight, twelve spikes) and insertion trajectories of constant velocities (5 mms−1, 10 mms−1,15 mms−1) and constant accelerations (5 mms−2, 10 mms−2, 15 mms−2) each in 5 samples. Furthermore, anatomical parameters (lumen diameter, tissue thickness) were recorded. Results There was no statistically significant difference in insertion forces neither between the trajectory groups, nor for variation of tissue fixation configurations. However, we observed a statistically significant increase in insertion forces for increasing number of spikes. The maximum mean peak forces for four, eight and twelve spikes were 6.4 ± 1.5 N, 13.6 ± 1.4 N and 21.7 ± 5.8 N, respectively. The 5th percentile of specimen lumen diameters and pierced tissue thickness were 24.1 mm and 2.8 mm, and the 95th percentiles 40.1 mm and 4.8 mm, respectively. Conclusion The setup enabled reliable biomechanical characterization of colon material, on the base of which design specifications for an endoscopic anastomosis device were derived. The axial implant closure unit must enable axial force transmission of at least 28 N (22 ± 6 N). Implant and applicator diameters must cover a range between 24 and 40 mm, and the implant gap, compressing anastomosed tissue, between 2 and 5 mm. |
| Databáze: | OpenAIRE |
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