Laparoscopic Sleeve Gastrectomy Versus Roux-Y-Gastric Bypass for Morbid Obesity—3-Year Outcomes of the Prospective Randomized Swiss Multicenter Bypass Or Sleeve Study (SM-BOSS)
| Autor: | Diana Vetter, Juergen Drewe, Marc Schiesser, Thomas Peters, Markus Gass, Philipp C. Nett, Yves Michael Borbély, Ralph Peterli, Bettina K. Wölnerhanssen, Marco Bueter, Christoph Beglinger, Bernd Schultes |
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| Přispěvatelé: | University of Zurich, Peterli, Ralph |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Time Factors medicine.medical_treatment Body Mass Index law.invention Postoperative Complications 0302 clinical medicine Randomized controlled trial law Prospective Studies Prospective cohort study Laparoscopy 610 Medicine & health Laparoscopic sleeve gastrectomy medicine.diagnostic_test Middle Aged 2746 Surgery Obesity Morbid Treatment Outcome Female 030211 gastroenterology & hepatology Roux y gastric bypass Switzerland RCT Adult Reoperation medicine.medical_specialty bariatric surgery 030209 endocrinology & metabolism Anastomosis Risk Assessment Morbid obesity 03 medical and health sciences Gastrectomy Weight Loss medicine Humans slevve gastrectomy gastric bypass 10217 Clinic for Visceral and Transplantation Surgery Analysis of Variance business.industry Anastomosis Roux-en-Y Randomized Controlled Trials Surgery morbid obesity Quality of Life business Follow-Up Studies |
| Zdroj: | Annals of Surgery Peterli, Ralph; Wölnerhanssen, Bettina Karin; Vetter, Diana; Nett, Philipp C.; Gass, Markus; Borbély, Yves Michael; Peters, Thomas; Schiesser, Marc; Schultes, Bernd; Beglinger, Christoph; Drewe, Juergen; Bueter, Marco (2017). Laparoscopic Sleeve Gastrectomy Versus Roux-Y-Gastric Bypass for Morbid Obesity-3-Year Outcomes of the Prospective Randomized Swiss Multicenter Bypass Or Sleeve Study (SM-BOSS). Annals of surgery, 265(3), pp. 466-473. Lippincott Williams & Wilkins 10.1097/SLA.0000000000001929 |
| ISSN: | 1528-1140 0003-4932 |
| DOI: | 10.1097/SLA.0000000000001929 |
| Popis: | OBJECTIVE Laparoscopic sleeve gastrectomy (LSG) is performed almost as often in Europe as laparoscopic Roux-Y-Gastric Bypass (LRYGB). We present the 3-year interim results of the 5-year prospective, randomized trial comparing the 2 procedures (Swiss Multicentre Bypass Or Sleeve Study; SM-BOSS). METHODS Initially, 217 patients (LSG, n = 107; LRYGB, n = 110) were randomized to receive either LSG or LRYGB at 4 bariatric centers in Switzerland. Mean body mass index of all patients was 44 ± 11 kg/m, mean age was 43 ± 5.3 years, and 72% of patients were female. Minimal follow-up was 3 years with a rate of 97%. Both groups were compared for weight loss, comorbidities, quality of life, and complications. RESULTS Excessive body mass index loss was similar between LSG and LRYGB at each time point (1 year: 72.3 ± 21.9% vs. 76.6 ± 20.9%, P = 0.139; 2 years: 74.7 ± 29.8% vs. 77.7 ± 30%, P = 0.513; 3 years: 70.9 ± 23.8% vs. 73.8 ± 23.3%, P = 0.316). At this interim 3-year time point, comorbidities were significantly reduced and comparable after both procedures except for gastro-esophageal reflux disease and dyslipidemia, which were more successfully treated by LRYGB. Quality of life increased significantly in both groups after 1, 2, and 3 years postsurgery. There was no statistically significant difference in number of complications treated by reoperation (LSG, n = 9; LRYGB, n = 16, P = 0.15) or number of complications treated conservatively. CONCLUSIONS In this trial, LSG and LRYGB are equally efficient regarding weight loss, quality of life, and complications up to 3 years postsurgery. Improvement of comorbidities is similar except for gastro-esophageal reflux disease and dyslipidemia that appear to be more successfully treated by LRYGB. |
| Databáze: | OpenAIRE |
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