Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
| Autor: | Radek Trojanec, Mariam Gachechiladze, Patrik Flodr, Tomáš Tichý, Jiří Ehrmann, Josef Skarda, Pavla Latalova, Maha Ibrahim, Zdenek Kolář |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Adult
Pathology medicine.medical_specialty Lung Neoplasms Antineoplastic Agents Case Report Diagnosis Differential Adult women Fatal Outcome Surgical oncology medicine Humans Neuroectodermal Tumors Primitive Lung business.industry Ewing's sarcoma Anemia medicine.disease Primitive neuroectodermal tumor medicine.anatomical_structure Oncology EWSR1 gene Immunohistochemistry Female Differential diagnosis Surgery Ewing’s sarcoma business |
| Zdroj: | World Journal of Surgical Oncology |
| ISSN: | 1477-7819 |
| DOI: | 10.1186/1477-7819-12-374 |
| Popis: | Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed. Electronic supplementary material The online version of this article (doi:10.1186/1477-7819-12-374) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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