Risk Factors for Clinically Relevant Postoperative Pancreatic Fistula (CR-POPF) after Distal Pancreatectomy: A Single Center Retrospective Study
| Autor: | Yong Fei Hua, Gao Qing Wang, Cai De Lu, Wei Jiang, Dipesh Kumar Yadav |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Article Subject medicine.medical_treatment RC799-869 Single Center Pancreatic Fistula Pancreatectomy Postoperative Complications Risk Factors medicine Humans Pancreas Retrospective Studies Pancreatic duct Univariate analysis Hepatology business.industry Gastroenterology Retrospective cohort study General Medicine Diseases of the digestive system. Gastroenterology medicine.disease Surgery Pancreatic Neoplasms medicine.anatomical_structure Pancreatic fistula Ligation business Research Article |
| Zdroj: | Canadian Journal of Gastroenterology and Hepatology, Vol 2021 (2021) Canadian Journal of Gastroenterology & Hepatology |
| ISSN: | 2291-2797 2291-2789 |
| DOI: | 10.1155/2021/8874504 |
| Popis: | Objectives. Clinically relevant postoperative pancreatic fistula (CR-POPF) is the considerable contributor to major complications after pancreatectomy. The purpose of this study was to evaluate the potential risk factor contributing to CR-POPF following distal pancreatectomy (DP) and discuss the risk factors of pancreatic fistula in order to interpret the clinical importance. Methods. In this retrospective study, 263 patients who underwent DP at Ningbo Medical Center Li Huili Hospital between January 2011 and January 2020 were reviewed in accordance with relevant guidelines and regulations. Patients’ demographics and clinical parameters were evaluated using univariate and multivariate analyses to identify the risk factors contributing to CR-POPF. P < 0.05 was considered statistically significant. Results. In all of the 263 patients with DP, pancreatic fistula was the most common surgical complication (19.0%). The univariate analysis of 18 factors showed that the patients with a malignant tumor, soft pancreas, and patient without ligation of the main pancreatic duct were more likely to develop pancreatic fistula. However, on multivariate analysis, the soft texture of the pancreas (OR = 2.381, 95% CI = 1.271–4.460, P = 0.001 ) and the ligation of the main pancreatic duct (OR = 0.388, 95% CI = 0.207–0.726, P = 0.002 ) were only an independent influencing factor for CR-POPF. Conclusions. As a conclusion, pancreatic fistula was the most common surgical complication after DP. The soft texture of the pancreas and the absence of ligation of the main pancreatic duct can increase the risk of CR-POPF. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text