Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
| Autor: | Ghanem Aljassem, Hazem Aljasem |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Ectopic Cushing’s
Pituitary gland medicine.medical_specialty Pathology medicine.medical_treatment 030209 endocrinology & metabolism Adrenocorticotropic hormone 030204 cardiovascular system & hematology Small-cell carcinoma Article 03 medical and health sciences Cushing syndrome 0302 clinical medicine Case report medicine Thoracotomy Lung business.industry Carcinoid tumor medicine.disease medicine.anatomical_structure Abdomen Surgery Radiology Presentation (obstetrics) business |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| DOI: | 10.1016/j.ijscr.2017.11.034 |
| Popis: | Highlights • Ectopic Cushing’s syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces a hormone called (ACTH). • Small cell carcinoma and carcinoid of the lung comprises half of its cases. • Ectopic cushing syndrome is a complicated medical problem especially when it comes to identification of the ectopic spot. • The surgical treatment could be curative when the spot is determined. Introduction Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing syndrome caused by a hidden lung carcinoid and how to manage it. Presentation of case Here we present a case of a 26 year old young male complains of increased weight and appetite, proximal muscle weakness, easy bruising and appearing of purple striae on his abdomen, with a final diagnosis of ACTH secreting lung carcinoid. Discussion The diagnosis was made by non-invasive radiological procedures (CT scan and MRI) and serological tests. The management consisted of medical treatment which was not useful, then bilateral adrenalectomy to limit the patient symptoms. The ectopic spot was finally detected and excised surgically through thoracotomy. After six months of follow up there was no recurrence, signs and symptoms of Cushing syndrome begin to disappear. Conclusion Ectopic cushing syndrome is a complicated medical problem especially when it comes to identification of the ectopic spot. The surgical treatment could be curative when the spot is determined. |
| Databáze: | OpenAIRE |
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