Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case–control study

Autor:	Moisés Hermilo Martínez-Osio, Alberto Chaparro-Sánchez, Luis Antonio Uribe-Noguez, Carla Ileana Arroyo-Anduiza, Jesús Gaytán-Martínez, Itzel Cruz-Grajales, Medardo Jerónimo-Morales, José Antonio Mata-Marín, Javier Enrique Cruz-Herrera, María de los Ángeles Berrospe-Silva
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Adult 0301 basic medicine medicine.medical_specialty lcsh:Medicine Comorbidity Logistic regression General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Interquartile range Internal medicine Diabetes mellitus HIV Seropositivity Prevalence medicine Humans 030212 general & internal medicine lcsh:Science (General) lcsh:QH301-705.5 Polypharmacy business.industry lcsh:R Case-control study HIV General Medicine Odds ratio Middle Aged medicine.disease Confidence interval Research Note 030104 developmental biology lcsh:Biology (General) Case-Control Studies business lcsh:Q1-390
Zdroj:	BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019) BMC Research Notes
ISSN:	1756-0500
DOI:	10.1186/s13104-019-4576-6
Popis:	Objective This study was to determine and compare the prevalences of polypharmacy and comorbidities in patients aged 50 years or older with those patients younger than 50 years in a Mexican population. Results One hundred and twenty-five patients were enrolled, 60 (48%) were aged 50 years or older. The median CD4+ cell counts were 509 cells/μL (interquartile range [IQR]: 324–730) for the older patients and 384 cells/μL (IQR: 262–562) (P = 0.021) for the younger patients. Viral suppression were significantly higher in the older group: 80% vs. 63% (P = 0.037). The number of comorbidities was significantly higher in the older group, with a median of 2 (IQR: 2–3) vs. 1 (IQR: 0–1) (P ≤ 0.001). After adjustment of the logistic regression model in the older group, the following comorbidities differed between the age groups: systemic arterial hypertension (odds ratio [OR]: 15.75; 95% confidence interval [CI] 3.49–71.05; P =
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131dd37ef97219838326196d85127354 http://link.springer.com/article/10.1186/s13104-019-4576-6 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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