G-compass: a web-based comparative genome browser between human and other vertebrate genomes
| Autor: | Ryuichi Sakate, Katsuhiko S. Murakami, Hao Zhang, Yoshiharu Sato, Tadashi Imanishi, Takashi Gojobori, Akihiro Matsuya, Yoshihiro Kawahara, Takeshi Itoh |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Statistics and Probability
animal structures DNA Copy Number Variations ved/biology.organism_classification_rank.species Genomics Computational biology Biology Biochemistry Genome Annotation Gene orders Databases Genetic Animals Humans Copy-number variation Model organism Molecular Biology Gene Genetics Internet ved/biology Genome Analysis Computer Science Applications Computational Mathematics Applications Note Computational Theory and Mathematics Vertebrates Human genome Software |
| Zdroj: | Bioinformatics |
| ISSN: | 1367-4811 1367-4803 |
| Popis: | Summary: G-compass is designed for efficient comparative genome analysis between human and other vertebrate genomes. The current version of G-compass allows us to browse two corresponding genomic regions between human and another species in parallel. One-to-one evolutionarily conserved regions (i.e. orthologous regions) between species are highlighted along the genomes. Information such as locations of duplicated regions, copy number variations and mammalian ultra-conserved elements is also provided. These features of G-compass enable us to easily determine patterns of genomic rearrangements and changes in gene orders through evolutionary time. Since G-compass is a satellite database of H-InvDB, which is a comprehensive annotation resource for human genes and transcripts, users can easily refer to manually curated functional annotations and other abundant biological information for each human transcript. G-compass is expected to be a valuable tool for comparing human and model organisms and promoting the exchange of functional information. Availability: G-compass is freely available at http://www.h-invitational.jp/g-compass/. Contact: t.imanishi@aist.go.jp |
| Databáze: | OpenAIRE |
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