The facile synthesis and bioactivity of a 3D nanofibrous bioglass scaffold using an amino-modified bacterial cellulose template
| Autor: | Ye Jianxia, Lijin Luo, Hong Yun, Cuilian Wen, Wu Junru, Qiu Yimei |
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| Rok vydání: | 2018 |
| Předmět: |
Scaffold
Materials science General Chemical Engineering 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Porous network 0104 chemical sciences chemistry.chemical_compound Tissue engineering Chemical engineering chemistry Bacterial cellulose Nanofiber 0210 nano-technology Bone regeneration |
| Zdroj: | RSC Advances. 8:14561-14569 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/c8ra00352a |
| Popis: | Porous bioglass (BG) scaffolds are of great importance in tissue engineering because of their excellent osteogenic properties for bone regeneration. Herein, we reported for the first time the use of amino-modified bacterial cellulose (NBC) as a template to prepare a three-dimensional (3D) nanofibrous BG scaffold by a facile modified sol–gel approach under ultrasonic treatment. The results suggested that the amino groups on the BC template could effectively promote the absorption of the deposited CaO and SiO2 precursors, and the as-obtained BG scaffold showed a 3D interconnected porous network structure consisting of nanofibers with a diameter of about 20 nm. Furthermore, the as-obtained BG scaffold showed very good bioactivity after being immersed in SBF for 7 days. This research provides a facile and efficient way to prepare a nanofibrous BG scaffold with 3D porous structure, which can be used as a promising candidate for biomedical applications. |
| Databáze: | OpenAIRE |
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