Role of hypertonic sodium lactate in traumatic brain injury management
| Autor: | Arie Ibrahim, Abdul Hafid Bajamal, Achmad Zuhro Ma'ruf, Muhammad Reza Arifianto |
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| Rok vydání: | 2018 |
| Předmět: |
Hypertonic sodium lactate
Energy demand Traumatic brain injury business.industry traumatic brain injury intracranial pressure 030208 emergency & critical care medicine Review Article General Medicine medicine.disease humanities Waste product 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Anesthesia medicine Sodium lactate Tonicity business Pathological 030217 neurology & neurosurgery Intracranial pressure |
| Zdroj: | Asian Journal of Neurosurgery |
| ISSN: | 2248-9614 1793-5482 |
| DOI: | 10.4103/ajns.ajns_10_17 |
| Popis: | Traumatic brain injury (TBI) following increased intracranial pressure (ICP) is a neuroemergency case which should be managed promptly to prevent secondary brain injury. This will lead to a condition called cerebral energy dysfunction which is an important determinant factor toward worse outcome. Lactate, which was historically known as an end waste product, now is considered as an alternative cerebral energetic fuel. Hypertonic sodium lactate (HSL) is a promising hyperosmolar fluid which serves not only to decrease ICP but also to readily supply exogenous lactate to fulfill increased cerebral energy demand. Pioneer studies have shown the harmlessness and usefulness of HSL in treating pathological condition including TBI. |
| Databáze: | OpenAIRE |
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