| Autor: |
Weizhou Zhang, Ronald J. Weigel, Ryan Askeland, Gabriel Velez, Fang Yuan, Wei Li, Qing Xie, Ryan Kolb, David Kusner, Nicholas Borcherding |
| Rok vydání: |
2023 |
| Popis: |
Supplementary Table S1. Index of genes upregulated or downregulated in basal-TIC tumors relative to luminal-TIC tumors. Supplementary Table S2. WNT5A CNV by PAM50 molecular subtype from samples with both RNAseq expression data and CNV (n=807). Figure S1: Verification of Illumina Array by reverse transcription real-time PCR analysis (Supplementary for Figure 1). Figure S2: Allelic loss of WNT5A led to decreased WNT5A expression in human breast-cancer specimens and mouse luminal epithelial cells. Figure S3: Schematic depiction of the purification procedure for different populations of mammary epithelial cells. Figure S4: Supplementary information of Figure 4. Figure S5: Heterozygous deletion of Wnt5a has no impact on normal mammary gland development. Figure S6: WNT5A induces the phosphorylation of SMAD2. Figure S7: Differential expression of canonical and noncanonical Wnt receptors in basal and luminal epithelial cells. Figure S8: RYK or SMAD2 expression does not correlate with metastasis-free survival. Figure S9: Schematic depiction of the major conclusions and explained in detail in the Discussion section. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
