Role of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and classification of lymphomas
| Autor: | Maria Angeles Torres Nieto, Manuel Perez-Miranda, Carlos Chavarría, Ignacio Fanjul, Francisco Javier García-Alonso, Javier Tejedor-Tejada, Beatriz Burgueño, Beatriz Madrigal Rubiales, Carlos de la Serna-Higuera |
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| Rok vydání: | 2020 |
| Předmět: |
Endoscopic ultrasound
Male medicine.medical_specialty Lymphoma medicine Suspected diagnosis Humans Adverse effect Endoscopic Ultrasound-Guided Fine Needle Aspiration Aged Retrospective Studies medicine.diagnostic_test business.industry Gastroenterology Mediastinum General Medicine medicine.disease body regions surgical procedures operative Fine-needle aspiration medicine.anatomical_structure Needles Abdomen Referral center Female Radiology business |
| Zdroj: | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. 113(6) |
| ISSN: | 1130-0108 |
| Popis: | Background: endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a safe and effective technique in the diagnosis of mediastinal and abdominal masses. However, the usefulness of EUS-FNA in the diagnosis and classification of lymphomas is controversial. The aim of this study was to determine the yield of EUS-FNA in the diagnosis and classification of lymphomas. Methods: a retrospective case series was performed in a tertiary referral center. All consecutive patients referred for EUS-FNA with a suspected diagnosis of lymphoma from March 2013 to June 2019 were included. Results: thirty-five patients (54.3 % women, median age 72 years) were included. The most frequent location of the node was the abdomen (67.9 %). Nodes were punctured using a 22-gauge (85.7 %) and 19-gauge needle (14.3 %) with a slow-pull technique. The number of passes performed were three or more in 82.9 % of patients. The samples were processed by the cellblock method. Adequate samples for immunohistochemical and molecular biological study were obtained in 33 (94.3 %) patients. EUS-FNA correctly diagnosed lymphoma in 30 out of 35 patients (85.7 %), and subclassification was determined in 23 patients (65.7 %). The most frequent diagnosis was non-Hodgkin lymphoma (85.7 %). There was one moderate adverse event (bleeding), which was resolved during the procedure. Conclusions: EUS-FNA may be a valuable technique in the evaluation of suspected lymphomas with an adequate diagnostic yield and a very low rate of adverse events. |
| Databáze: | OpenAIRE |
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