Prophylaxis of acute viral hepatitis by immune serum globulin, hepatitis B vaccine, and health education: a sixteen year study of Japan overseas cooperation volunteers
| Autor: | Isao Ebisawa, Hiroshi Naruto, Hiroshi Ohara |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Viral Hepatitis Vaccines Volunteers medicine.medical_specialty Hepatitis B vaccine Hepatitis Viral Human Japan Virology Internal medicine medicine Humans Hepatitis B Vaccines Health Education Hepatitis Hepatitis A Vaccines Travel biology business.industry Incidence Immunization Passive Hepatitis A Hepatitis B medicine.disease Hepatitis C Vaccination Infectious Diseases Immunology Acute Disease biology.protein Parasitology Female Viral disease Antibody Morbidity Viral hepatitis business Hepatitis A Virus Human |
| Zdroj: | The American journal of tropical medicine and hygiene. 56(1) |
| ISSN: | 0002-9637 |
| Popis: | From 1978 to 1993 a study of acute viral hepatitis contracted by the Japan Overseas Cooperation Volunteers (JOCV) during their assignments in tropical and subtropical countries was conducted. Of 10,509 subjects in this study, 240 cases of acute viral hepatitis were confirmed (hepatitis A = 139, hepatitis B = 72, and non-A, non-B hepatitis = 29). The annual morbidity was 5.1% in 1978 and 4.9% in 1979, with hepatitis A accounting for 80% of the cases. However, it decreased significantly after the prophylactic inoculation with immune serum globulin (ISG) was started in 1980. A significant decrease of hepatitis B from 1.2% in 1980 to 0.1% in 1990 was also seen after vaccination was introduced for all volunteers in 1988. Health education concerning food and water sanitation, and providing general information on viral hepatitis, was also conducted throughout this period. These results indicate that acute viral hepatitis could be successfully prevented in the JOCV with a combination of ISG, hepatitis B vaccination, and health education. |
| Databáze: | OpenAIRE |
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