US-guided percutaneous microwave ablation for hyperthyroidism and immediate treatment response evaluation with contrast-enhanced ultrasound
Autor: | Hui-Xiong Xu, Hui-Li Zhang, Jing-E Zhu, Song-Yuan Yu |
---|---|
Rok vydání: | 2021 |
Předmět: |
Adult
Primary Hyperthyroidism endocrine system medicine.medical_specialty Percutaneous endocrine system diseases Physiology medicine.medical_treatment 030209 endocrinology & metabolism Hyperthyroidism Thyroid function tests Iodine Radioisotopes 03 medical and health sciences 0302 clinical medicine Antithyroid Agents Physiology (medical) Humans Medicine Microwaves Methimazole medicine.diagnostic_test business.industry Thyroid Microwave ablation Hematology Ablation Surgery Treatment Outcome medicine.anatomical_structure 030220 oncology & carcinogenesis Hypermetabolism Female Thyroid function Cardiology and Cardiovascular Medicine business |
Zdroj: | Clinical Hemorheology and Microcirculation. 79:435-444 |
ISSN: | 1875-8622 1386-0291 |
Popis: | Hyperthyroidism is a common disease mainly manifested by hyperexcitability of multiple systems and hypermetabolism. Currently, antithyroid drugs (ATDs), radioiodine therapy (RIT), and surgery are mainly used in the clinical treatment for primary hyperthyroidism. We reported a case of a 28-year-old female who received a novel treatment for primary hyperthyroidism. This patient had poor control of thyroid function while taking ATD, and her oral Methimazole (MMI) dose varied repeatedly between 20 mg qd and 15 mg qd, failing to maintain a stable status. To minimize the possible complication and to achieve drug reduction or withdrawal, she refused RIT and surgery and showed up in our department. The patient, diagnosed with Graves’ disease (GD) and met the surgical indication after systematic clinical evaluation, was subject to ultrasound-guided percutaneous microwave ablation (MWA) of the partial thyroid gland with continuous oral administration of 20 mg qd MMI. The post-ablation condition was stable and the patient was discharged 2 days after the operation. Thyroid ultrasound and serum thyroid function test were examined regularly after ablation and the MMI dosage was gradually reduced according to the results of the biochemical examination. Five weeks after the operation, the patient completely discontinued the medication. Ultrasound-guided percutaneous microwave ablation is minimally invasive, safe, and effective, and has potential to be an alternative treatment besides the 3 classical treatments of hyperthyroidism. |
Databáze: | OpenAIRE |
Externí odkaz: | |
Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |