Quantitative assessment of allergic shiners in children with allergic rhinitis
Autor: | Shih-Hsuan Chiu, Kuo-Hung Lin, Che-Yen Wen, Li-Chieh Wang, Yao-Hsu Yang, Chien-Han Chen, Yu-Tsan Lin, Jyh-Hong Lee, Bor-Luen Chiang |
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Rok vydání: | 2009 |
Předmět: |
Male
medicine.medical_specialty Allergy Rhinitis Allergic Perennial Immunology Sensitivity and Specificity Severity of Illness Index Eye symptoms Quality of life Surveys and Questionnaires Severity of illness medicine Quantitative assessment Humans Immunology and Allergy Diagnosis Computer-Assisted Prospective Studies Child Prospective cohort study business.industry Reproducibility of Results Rhinitis Allergic Seasonal Reference Standards Weights and Measures medicine.disease Dermatology Surgery El Niño Chronic Disease Cohort Female business |
Zdroj: | Journal of Allergy and Clinical Immunology. 123:665-671.e6 |
ISSN: | 0091-6749 |
Popis: | The knowledge on allergic shiners is extremely limited. A conceivable tool able to quantify allergic shiners has not been established.We sought to determine the significance and changeability of allergic shiners through our newly developed computerized method.We developed a novel computerized method to measure allergic shiners and enrolled a cohort of children with or without allergic rhinitis. Children with allergic rhinitis were prospectively assessed. A standardized digital photograph was taken during each visit, and a modified Pediatric Rhinoconjunctivitis Quality of Life Questionnaire was completed. Subject global assessment for nose symptoms and subject global assessment for eye symptoms (SGAE) were self-recorded daily.We included 126 children with allergic rhinitis and 123 healthy control subjects. One hundred three (82%) participants with allergic rhinitis completed at least 4 prospective assessments. Shiners were darker (P.001) and larger (P.001) in children with allergic rhinitis. Darkness and sizes of allergic shiners were paradoxically inversely correlated (P = .02). Darkness of allergic shiners positively correlated with the duration of allergic rhinitis, practical problem scores, and SGAE values (P = .02, P = .004, and P = .002, respectively), but sizes of allergic shiners did not. Shiners were found to be darker in children with scores of eye symptoms of greater than 6, scores of practical problems of greater than 5, and SGAE values of greater than 0 (P = .02, P.001, and P = .003, respectively), whereas shiners were larger in children with scores of other symptoms of greater than 9 and activity limitations of greater than 4 (P = .02 and P = .002, respectively).Computer-analyzed allergic shiners correlate with the chronicity and severity of allergic rhinitis. |
Databáze: | OpenAIRE |
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