Nationwide survey for current clinical status of amniocentesis and maternal serum marker test in Japan
| Autor: | Yasuko Yamanouchi, Hideaki Sawai, Hideaki Masuzaki, Makoto Kanai, Hidehiko Miyake, Yoichi Matsubara, Naoko Arimori, Fumio Takada, Shigehito Yamada, Yuka Ozasa, Fumiki Hirahara, Akihiko Sekizawa, Yosuke Fujii, Haruhiko Sago, Koji Kugu |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Health Personnel Genetic counseling MEDLINE 030105 genetics & heredity Biology Nationwide survey 03 medical and health sciences Japan Pregnancy Prenatal Diagnosis Surveys and Questionnaires Genetics medicine Humans Genetic Testing Genetics (clinical) Genetic testing medicine.diagnostic_test Obstetrics Professional-Patient Relations Test (assessment) Developmental genetics Health Care Surveys Amniocentesis Female Biomarkers Serum markers |
| Zdroj: | Journal of Human Genetics. 61:879-884 |
| ISSN: | 1435-232X 1434-5161 |
| Popis: | Prenatal testing has been provided in Japan over the past several decades. However, it is difficult to assess the clinical status of amniocentesis (AC) and maternal serum markers (MSM) because obstetricians can perform these tests without registration. This study aims to investigate the current clinical status of AC and MSM in Japan. We conducted a questionnaire study that was intended for a total of 5622 Japanese obstetrics/gynecology facilities during October 2013 to January 2014. The response rate was 40.8% (2295/5622). Of the 2295 facilities, 864 performed MSM (37.7%), 619 performed AC (27.0%) and 412 performed both (18.0%). The average number of MSM tests was 2.0 per month (range 0-52), and the average number of AC tests was 2.4 per month (range 0-30). Involvement of genetic professionals, such as clinical geneticists (CGs) and certified genetic counselors (CGCs), contribute to a content-rich explanation and management of difficult issues and lengthened the explanation time. Nevertheless, relatively few facilities employed these specialists (MSM: 96/864 and AC: 128/619). This is the first study to highlight the current clinical status of AC and MSM tests in Japan. Active involvement of CGs and CGCs can provide more appropriate genetic counseling for prenatal tests. |
| Databáze: | OpenAIRE |
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