Quantitative Analysis of Chondroitin Sulfate in Tear Fluids following Laser in situ Keratomileusis
| Autor: | Masaya Nishio, Kiyomi Arai |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male In situ medicine.medical_specialty genetic structures medicine.medical_treatment Keratomileusis Laser In Situ Enzyme-Linked Immunosorbent Assay Keratomileusis Cornea Cellular and Molecular Neuroscience chemistry.chemical_compound Chondroitin 6-Sulfate Ophthalmology Myopia medicine Humans Chondroitin sulfate Wound Healing business.industry Chondroitin Sulfates Astigmatism LASIK General Medicine eye diseases Sensory Systems Surgery chemistry Tears Female sense organs business Chondroitin 4 sulfate Wound healing Quantitative analysis (chemistry) |
| Zdroj: | Ophthalmic Research. 38:274-279 |
| ISSN: | 1423-0259 0030-3747 |
| DOI: | 10.1159/000095770 |
| Popis: | Purpose: To report chondroitin sulfate (CS) concentrations in tear fluid following laser in situ keratomileusis (LASIK). Methods: Fourteen eyes that underwent LASIK were enrolled. We measured the CS isomers chondroitin 4 sulfate and chondroitin 6 sulfate using an enzyme-linked immunosorbent assay preoperatively and postoperatively on days 1 and 4, week 1, and 1 and 3 months. Results: The chondroitin 4 sulfate concentration remained unchanged from preoperative values. The chondroitin 6 sulfate concentration increased temporarily 1 day postoperatively and gradually decreased thereafter. Conclusions: CS in tear fluids participates in wound healing after LASIK. Clarifying its role in tear fluids will contribute to improved LASIK outcomes. |
| Databáze: | OpenAIRE |
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