Association of choroidal thickness with early stages of diabetic retinopathy in type 2 diabetes
| Autor: | Zhi-Jun Shen, Xiufen Yang, Wen-Wen Wei, Jun Xu, Chong-Yang She, Ningpu Liu, Wan-Lu Zhu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
choroidal thickness Ocular health medicine.medical_specialty diabetic choroidopathy Type 2 diabetes 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Clinical Research Ophthalmology medicine business.industry Diabetic retinopathy medicine.disease Control subjects eye diseases diabetic retinopathy 030104 developmental biology lcsh:RE1-994 030221 ophthalmology & optometry Multiple linear regression analysis sense organs business Body mass index Retinopathy Non diabetic |
| Zdroj: | International Journal of Ophthalmology, Vol 10, Iss 4, Pp 613-618 (2017) |
| ISSN: | 2227-4898 2222-3959 |
| Popis: | AIM: To assess the correlation between choroidal thickness (CT) and the early stages of diabetic retinopathy (DR) in type 2 diabetic patients. METHODS: We divided 83 diabetic patients (51-80 years of age; 50 females) into non diabetic retinopathy group (NDR) and mild/moderate nonproliferative diabetic retinopathy (NPDR) group, and compared them with 26 non-diabetic control subjects (51-78 years of age; 16 females). Subfoveal choroidal thickness (SFCT) and parafoveal choroidal thickness (PFCT) were measured using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Ocular health status, disease duration, body mass index, and hemoglobin A1c (HbA1c) were recorded. RESULTS: The mean ages of the NDR, NPDR, and control groups were 68.0±6.9y, 67.8±6.4y, and 65.1±6.3y, respectively (P=0.17). Pearson correlation of the right and left eyes for the control subjects was 0.95 and for the NDR subjects was 0.93. SFCT for the right eyes of the controls was 252.77± 41.10 μm, which was significantly thicker than that of the right eyes in NDR group (221.51±46.56 μm) and the worse eyes of the NPDR group (207.18±61.87 μm; ANOVA, P |
| Databáze: | OpenAIRE |
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