Dengue outbreaks: a constant risk for Reunion Island. Results from a seroprevalence study among blood donors

Autor: Alain Michault, D Polycarpe, François Schooneman, Sophie Larrieu, Laurent Filleul, Eric D'Ortenzio
Rok vydání: 2013
Předmět:
Zdroj: Transactions of the Royal Society of Tropical Medicine and Hygiene. 108:57-59
ISSN: 1878-3503
0035-9203
DOI: 10.1093/trstmh/trt110
Popis: Background Immunity against dengue virus (DENV) on Reunion Island could play an important role in the risk of dengue outbreaks but is rather unknown. A study was performed to estimate seroprevalence of antibodies against DENV among blood donors. Methods An age- and sex-stratified sample of 1825 sera was randomly selected. Results Overall seroprevalence was 3.1% (95% CI: 2.2-3.9%); seroprevalence increased with age and was much higher in women than in men. Conclusion The low level of herd immunity is consistent with the absence of an endemic circulation of DENV, and makes it probable that Reunion Island will face future outbreaks.
Databáze: OpenAIRE