Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil
| Autor: | A. T. S. Silva, P. C. P. Poblete, Luis B. Oliveira, F. T. Rocha, Poliana de Oliveira Figueiredo, Erna Geessien Kroon, Jaqueline Silva de Oliveira, G. P. Domingos, Betania Paiva Drumond, D. C. Duarte, Paula Eillanny Silva Marinho, Danilo Bretas de Oliveira, Jônatas Santos Abrahão, Giliane de Souza Trindade, Cláudio A. Bonjardim |
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| Rok vydání: | 2018 |
| Předmět: |
Primates
0301 basic medicine medicine.medical_specialty Health Toxicology and Mutagenesis Biology Communicable Diseases Emerging Virus Disease Outbreaks 03 medical and health sciences Aedes Yellow Fever Genotype medicine Animals Humans Vulnerable population Ecology Public health Yellow fever Outbreak medicine.disease Virology 030104 developmental biology Animal ecology South american Yellow fever virus Brazil |
| Zdroj: | EcoHealth. 15:864-870 |
| ISSN: | 1612-9210 1612-9202 |
| DOI: | 10.1007/s10393-018-1364-z |
| Popis: | At the end of 2016, Brazil experienced an unprecedented yellow fever (YF) outbreak. Clinical, molecular and ecological aspects of human and non-human primate (NHP) samples collected at the beginning of the outbreak are described in this study. Spatial distribution analyses demonstrated a strong overlap between human and NHP cases. Through molecular analyses, we showed that the outbreak had a sylvatic origin, caused by the South American genotype 1 YFV, which has already been shown to circulate in Brazil. As expected, the clusters of cases were identified in regions with a low vaccination coverage. Our findings highlight the importance of the synchronization of animal surveillance and health services to identify emerging YF cases, thereby promoting a better response to the vulnerable population. |
| Databáze: | OpenAIRE |
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