The relationship between serum uric acid level and uric acid/creatinine ratio with chronic obstructive pulmonary disease severity (stable or acute exacerbation) and the development of cor pulmonale
| Autor: | İsmail Hakkı Tuncez, Emre Kir, Yusuf Taha Gullu, Atilla Guven Atici, Nurhan Koksal |
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| Rok vydání: | 2020 |
| Předmět: |
Spirometry
medicine.medical_specialty Exacerbation Hypertension Pulmonary 030204 cardiovascular system & hematology Gastroenterology Hypoxemia 03 medical and health sciences chemistry.chemical_compound Pulmonary Disease Chronic Obstructive 0302 clinical medicine Pulmonary Heart Disease Internal medicine medicine Outpatient clinic Humans 030212 general & internal medicine COPD Creatinine medicine.diagnostic_test business.industry General Medicine medicine.disease Pulmonary hypertension respiratory tract diseases Uric Acid chemistry Uric acid medicine.symptom business |
| Zdroj: | International journal of clinical practiceREFERENCES. 75(8) |
| ISSN: | 1742-1241 |
| Popis: | BACKGROUND There are studies reporting that uric acid elevation is a marker for hypoxemia and pulmonary hypertension secondary to some diseases. AIM The aim of this study is to investigate the relationship between serum uric acid level and uric acid/creatinine ratio with chronic obstructive pulmonary disease (COPD) exacerbation, hypoxemia in exacerbation and development of cor pulmonale. METHODS A total of 96 COPD patients who were admitted to Ondokuz Mayis University Faculty of Medicine emergency department and Chest Diseases outpatient clinic and whose written consent was obtained were included in our study. Forty-three of these patients were in the period of exacerbation (Group 1), and 53 were in the stable period (Group 2). Complete blood count, blood biochemistry (including serum uric acid level) and arterial blood gas analysis were performed in our patients. In addition, spirometry and echocardiography findings were examined. RESULTS Serum uric acid level of patients in the period of exacerbation group (Group 1) was 6.97 ± 1.34 and in stable COPD group (Group 2) was 4.30 ± 1.01 (P |
| Databáze: | OpenAIRE |
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