| Autor: |
Diego Faccone, Juan M. de Mendieta, Ezequiel Albornoz, Magali Chavez, Fabiana Genero, Mariano Echegorry, Paola Ceriana, Andrea Mora, Christine Seah, Alejandra Corso, Roberto G. Melano, Fernando Pasteran |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Antimicrob Agents Chemother |
| ISSN: |
1098-6596 |
| Popis: |
A ceftazidime-avibactam-resistant KPC-producing Pseudomonas aeruginosa strain was isolated in Argentina from a tracheal aspirate. The patient was treated with ceftazidime-avibactam in combination with other agents for 130 days. Whole-genome sequencing of P. aeruginosa identified a D179Y substitution in the Ω loop of KPC-3, corresponding to KPC-31, integrated at the chromosome. The strain belonged to the sequence type 235/O11 (ST235/O11) high-risk clone. Evaluation of carbapenemase detection assays most used by clinical laboratories failed to identify the isolate as a KPC producer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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