Correlation between diabetes mellitus and periodontitis in Taiwan: A nationwide cohort study
| Autor: | Chien-Ying Lee, Tung-Han Tsai, Yu-Hsiang Kuan, Kuang-Hua Huang, Ya-Fang Tsai, Chih Jaan Tai |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Databases Factual Endocrinology Diabetes and Metabolism Taiwan 030209 endocrinology & metabolism Arthritis Rheumatoid Young Adult 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine Diabetes mellitus Diabetes Mellitus Internal Medicine medicine Humans 030212 general & internal medicine Periodontitis Aged Dyslipidemias Retrospective Studies Proportional hazards model business.industry Incidence Hazard ratio Retrospective cohort study General Medicine Middle Aged medicine.disease Confidence interval Hypertension Female business Dyslipidemia Cohort study |
| Zdroj: | Diabetes Research and Clinical Practice. 150:245-252 |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2019.03.019 |
| Popis: | Aims The mechanism underlying the association of diabetes mellitus (DM) and periodontitis is not clear. This study aimed to investigate the correlation between DM and periodontitis. Methods This study was a retrospective cohort study, which conducted based on the Taiwan National Health Insurance Research Database. The study subjects were 39,384 new-onset DM patients who aged above 20 years old from 2005 to 2012. To avoid selection bias, we applied propensity score matching to obtain patients without DM, as the control group. Cox proportional hazard model was used to analyze the risk of periodontitis in patients with DM. Results After controlling for related variables, Patients with DM had a higher risk for periodontitis compared with the patients without DM (adjusted hazard ratios [aHR] = 1.04, 95% confidence interval [CI]: 1.01–1.08). Patients with hypertension (HTN) had no higher risk for periodontitis (aHR = 0.96, 95% CI: 0.92–1.00). Patients with dyslipidemia and rheumatoid arthritis (RA) patients both had a higher risk for periodontitis (aHR = 1.26, 95% CI: 1.19–1.34; aHR = 1.41, 95% CI: 1.19–1.67). Conclusions There is a correlation between DM and periodontitis. Patients with DM may have a higher risk of incident periodontitis. Besides, age, HTN, dyslipidemia, and RA are also associated with incident periodontitis. |
| Databáze: | OpenAIRE |
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