Cancer and Thrombosis: New Treatments, New Challenges
Autor: | Anders E.A. Dahm |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Review 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Neoplasms medicine Humans cancer 030212 general & internal medicine Intensive care medicine anticoagulation thrombosis treatment business.industry Urogenital Cancers Anticoagulants Cancer Venous Thromboembolism Heparin Heparin Low-Molecular-Weight medicine.disease Thrombosis Clinical trial Oral anticoagulant Medicine prophylaxis business Venous thromboembolism medicine.drug |
Zdroj: | Medical Sciences, Vol 9, Iss 41, p 41 (2021) Medical Sciences |
ISSN: | 2076-3271 |
Popis: | The direct-acting oral anticoagulant (DOAC) has become an alternative to low-molecular-weight heparin (LMWH) for treatment and prophylaxis of venous thromboembolism (VTE) in cancer patients. The clinicians are, however, faced with difficult decisions regarding DOAC treatment: Which patients cannot use DOACs? Should incidental VTE be treated similar to symptomatic VTE? Is it safe to give DOACs to patients with gastrointestinal or urogenital cancers? How about drug–drug interactions? Should all cancer patients receive thromboprophylaxis? Is arterial thrombosis a problem? The current article reviews the available literature regarding these questions and aims to provide practical solutions based on data from the clinical trials and new guidelines. |
Databáze: | OpenAIRE |
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