Distribution of binding sites for 125I-labeled alpha-bungarotoxin in normal and deafferented antennal lobes of Manduca sexta
| Autor: | Barbara C. Osmond, Linda Hall, John G. Hildebrand |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
animal structures Moths Biology Insect central nervous system chemistry.chemical_compound Internal medicine medicine Animals Distribution (pharmacology) Receptors Cholinergic Binding site Receptor Acetylcholine receptor Denervation Afferent Pathways Multidisciplinary Alpha-Bungarotoxin fungi Brain Bungarotoxins biology.organism_classification Cell biology Lepidoptera Endocrinology chemistry Manduca sexta Synapses Research Article |
| Zdroj: | Proceedings of the National Academy of Sciences. 76:499-503 |
| ISSN: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.76.1.499 |
| Popis: | 125I-Labeled alpha-bungarotoxin has been used to determine the distribution of putative acetylcholine receptors in normal and chronically deafferented antennal lobes in the brain of the moth Manduca sexta. Toxin-binding sites are confined to synaptic regions in deafferented lobes. These findings suggest that receptors can develop in the insect central nervous system independently of normal synaptic influences. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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