Hemodynamic changes after administration of mannitol measured by a noninvasive cardiac output monitor
| Autor: | Nikki Sabharwal, Zulfiqar Ali, G. S. Umamaheswara Rao, M. Radhakrishnan |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Cardiac output Cardiac index Hemodynamics Blood Pressure Electrocardiography Heart Rate Internal medicine Monitoring Intraoperative medicine Intravascular volume status Electric Impedance Humans Mannitol Cardiac Output Diuretics business.industry Stroke Volume Stroke volume Middle Aged Urodynamics Anesthesiology and Pain Medicine Blood pressure medicine.anatomical_structure Anesthesia Cardiology Vascular resistance Surgery Female Neurology (clinical) business Craniotomy medicine.drug |
| Zdroj: | Journal of neurosurgical anesthesiology. 21(3) |
| ISSN: | 1537-1921 |
| Popis: | Mannitol is the most commonly used hyperosmotic agent in neurosurgery. Being an agent that increases intravascular volume by withdrawing water from the brain, it may cause significant changes in stroke volume (SV), cardiac output (CO), systemic vascular resistance and blood pressure. In this study, we monitored the hemodynamic changes in response to a single dose of mannitol by using a noninvasive CO monitor based on the thoracic electrical bioimpedance technique, in patients undergoing craniotomy. Eleven adult patients undergoing elective craniotomy received mannitol 1.0 g/kg 15 minutes before dural opening. The following hemodynamic variables were recorded: heart rate, systolic blood pressure, diastolic blood pressure, SV, CO, and cardiac index. The measurements were made before the administration of mannitol, at 1, 2, 5, 10, 15, 20, 25, 30, 35, 40, and 45 minutes after the termination of the mannitol infusion. Urine output was measured at 10, 20, 30, 40, 50, 60, 90, and 120 minutes after termination of the mannitol infusion. Heart rate values from 25 to 45 minutes were significantly lower compared with the premannitol values (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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