Suspected anaphylaxis after intravenous administration of cefuroxime (Zinacef) in two dogs, with descriptions of arterial blood gas abnormalities over time
| Autor: | Hannah Leigh, Ambra Panti, Gudrun Schöffmann, Hulda Harðardottir |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Tachycardia
Allergy 040301 veterinary sciences Terbutaline Anaesthesia 0403 veterinary science Dogs medicine Dexamethasone General Veterinary Antimicrobials business.industry 0402 animal and dairy science 04 agricultural and veterinary sciences Chlorphenamine medicine.disease 040201 dairy & animal science medicine.anatomical_structure Anesthesia Arterial blood medicine.symptom business Cefuroxime Thoracic wall Anaphylaxis medicine.drug |
| Zdroj: | Leigh, H, Hardardottir, H, Schoffmann, G & Panti, A 2019, ' Suspected anaphylaxis after intravenous administration of cefuroxime (Zinacef) in two dogs, with descriptions of arterial blood gas abnormalities over time ', Vet Record Case Reports . https://doi.org/10.1136/vetreccr-2019-000922 |
| ISSN: | 2052-6121 |
| DOI: | 10.1136/vetreccr-2019-000922 |
| Popis: | Two cases of suspected anaphylaxis occurred in our hospital within 2 weeks of each other. The first, a 6-year 4-month-old Border Collie presented for thoracic wall resection. Once anaesthetised, 20mg/kg of intravenous cefuroxime (Zinacef 75mg/ml, GlaxoSmithKline UK, UK) was administered slowly for prophylactic antibiosis. Ten minutes after administration was completed – desaturation occurred alongside tachycardia, hypotension and apnoea. Chest compliance was extremely poor, with minimal chest movement. Treatment includedintermittent positive pressure ventilation, intravenous fluids, terbutaline, adrenaline and dexamethasone. The second case, a 5-year 8-month old Lhasa Apso presented for elective orthopaedic surgery. Intravenous cefuroxime (Zinacef 75mg/ml, GlaxoSmithKline UK, UK) was again administered slowly for prophylactic antibiosis; however, it is uncertain whetherthe patient received the full dose of 20mg/kg. Mid administration tachycardia, tachypnoea and hypotension occurred – alongside poor chest compliance. Cefuroxime administration was stopped, the fluid line disconnected and treatment with chlorphenamine given. |
| Databáze: | OpenAIRE |
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