Impact of hospital-wide infection rate, invasive procedures use and antimicrobial consumption on bacterial resistance inside an intensive care unit

Autor: R. P. Dos Santos, Thalita Silva Jacoby, Leila Beltrami Moreira, P. Guzatto, Ricardo de Souza Kuchenbecker, Lucas Magedanz
Rok vydání: 2010
Předmět:
Zdroj: Journal of Hospital Infection. 75:23-27
ISSN: 0195-6701
DOI: 10.1016/j.jhin.2009.11.021
Popis: We performed a 30-month ecological study to determine the impact of hospital-wide antibiotic consumption, invasive procedure use and hospital-acquired infections (HAIs) on antibiotic resistance in an intensive care unit (ICU). Microbiological isolates from ICU patients with established diagnosis of hospital infection were monitored throughout the study. Overall hospital consumption per 100 patient-days of piperacillin-tazobactam, fluoroquinolones and cephalosporins increased from 1.9 to 2.3 defined daily doses (DDD) (P
Databáze: OpenAIRE