Mitogenic activity of staphylococcal exfoliative toxin
| Autor: | B A Morlock, A D Johnson, Leonard Spero |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Staphylococcus aureus
Bacterial Toxins Immunology Mice Nude Spleen Enterotoxin Biology Lymphocyte Activation Staphylococcal Exfoliative Toxin medicine.disease_cause Microbiology Mice medicine Animals Lymphocytes Mitogenic activity Cells Cultured Simple sugar Infectious Diseases medicine.anatomical_structure Mitogen-activated protein kinase biology.protein Parasitology Exfoliatin Mitogens Research Article |
| Zdroj: | Infection and Immunity. 30:381-384 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.30.2.381-384.1980 |
| Popis: | Exfoliative toxin from Staphylococcus aureus was mitogenic for murine spleen cells. It was primarily active on T lymphocytes but also significantly stimulated B cells from the spleens of nude mice. The mitogenicity was not affected by simple sugar or alpha-methylpyranosides. N-acetylglucosamine and N-acetylgalactosamine inhibited its effect. Exfoliatin was as powerful a mitogen as the enterotoxins of S. aureus. Some significant differences between the mitogenic activity of the two toxins were demonstrated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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