Effect of Amino Acid Imbalance on Course of Lansing Poliomyelitis in Mice
| Autor: | A. F. Rasmussen, Paul F. Clark, S. N. Gershoff, C. A. Elvehjem |
|---|---|
| Rok vydání: | 1952 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Methionine Tryptophan Phenylalanine Biology Antifibrinolytic Agents General Biochemistry Genetics and Molecular Biology Amino acid Mice chemistry.chemical_compound Endocrinology chemistry Biochemistry Internal medicine Casein Antifibrinolytic agent medicine Animals Choline Amino Acids Leucine Poliomyelitis |
| Zdroj: | Experimental Biology and Medicine. 81:484-486 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-81-19917 |
| Popis: | Summary1. A decreased susceptibility to Lansing poliomyelitis, characterized by prolonged incubation and survival times, has been observed in mice fed excess methionine. To obtain this effect fully, a continuous period of high methionine intake was necessary prior to inoculation. 2. The addition of excess methionine to low tryptophan rations containing 6-methyl tryptophan resulted in a more marked protection against Lansing infection in mice than when the same amounts of methionine or 6-methyl tryptophan were fed alone. |
| Databáze: | OpenAIRE |
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