The association between extended spectrum beta-lactamase (ESBL) and ampicillin C (AmpC) beta-lactamase genes with multidrug resistance in Escherichia coli isolates recovered from turkeys in Brazil
| Autor: | Priscilla K. Koerich, Patrícia Giovana Hoepers, João Paulo Zuffo, Daise Aparecida Rossi, PL Silva, E C Valadares Júnior, B C Ferreira, Belchiolina Beatriz Fonseca |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Turkeys medicine.medical_treatment 030106 microbiology Erythromycin Biology medicine.disease_cause beta-Lactamases Microbiology 03 medical and health sciences Antibiotic resistance Bacterial Proteins Ampicillin Drug Resistance Bacterial Escherichia coli Prevalence polycyclic compounds medicine Animals Escherichia coli Infections Poultry Diseases General Medicine biochemical phenomena metabolism and nutrition Amoxicillin bacterial infections and mycoses Anti-Bacterial Agents Cephalosporins Multiple drug resistance Phenotype 030104 developmental biology Beta-lactamase Animal Science and Zoology Ceftiofur Brazil Food Science medicine.drug |
| Zdroj: | British Poultry Science. 59:396-401 |
| ISSN: | 1466-1799 0007-1668 |
| DOI: | 10.1080/00071668.2018.1468070 |
| Popis: | 1. The aim of this study was to analyse the association between Escherichia coli isolates recovered from turkeys and the expression of beta-lactamase genes, such as extended spectrum beta-lactamase (ESBL) and ampicillin class C (AmpC). The phenotype of the resistance profile was examined using the association between amoxicillin and ceftiofur resistance. 2. Results showed that 84% from the turkey isolates harboured 4 or 5 genes associated with the CoIV plasmid. In an antibiogram test, 82% of the isolates were multidrug-resistant, the highest levels of resistance being against erythromycin (99%) and amoxicillin (76.1%). ESBL-positive groups were 31% positive for the ctx-m-2 gene, 6.8% were positive for ctx-m-8 and 70% harboured the tem wild gene. 3. All positive isolates from the AmpC beta-lactamase-positive group harboured the cmy-2 gene. The presence of the cmy-2 gene was associated with both the CTX-group genes and resistance to ceftiofur. 4. There was a high prevalence of avian pathogenic E. coli in suspected cases of colibacillosis in turkeys and a high antimicrobial resistance index. The results highlighted the risk of ceftiofur resistance and the presence of both ESBL and AmpC beta-lactamase E. coli in the turkey production chain. |
| Databáze: | OpenAIRE |
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