Low protein alimentation normalizes renal haemodynamic response to acute protein ingestion in type 1 diabetic children
| Autor: | Anastasio P, S Coppola, Alessandra F. Perna, R. Torella, Capodicasa G, N. G. De Santo, Giovambattista Capasso, Teresa Salvatore, Carmelo Giordano, Pietro Castellino |
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| Přispěvatelé: | Castellino, P, DE SANTO, Ng, Capasso, Giovambattista, Anastasio, Pietro, Coppola, S, Capodicasa, G, Perna, Alessandra, Torella, R, Salvatore, Teresa, Giordano, C. |
| Rok vydání: | 1989 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Low protein Adolescent Protein diet Haemodynamic response medicine.medical_treatment Clinical Biochemistry High-protein diet medicine.disease_cause Biochemistry Renal Circulation Basal (phylogenetics) Low-protein diet Internal medicine medicine Humans Insulin Protein meal Child business.industry Hexosamines General Medicine Glucagon Diabetes Mellitus Type 1 Endocrinology Fructosamine Protein ingestion Female Dietary Proteins business Glomerular Filtration Rate |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1365-2362 0014-2972 |
| DOI: | 10.1111/j.1365-2362.1989.tb00310.x |
| Popis: | The effect of an acute protein load (2 g kg‐1bodyweight [BW]) was studied in nine type 1 diabetic children. Patients were maintained on two different dietary regimens. In study one, patients were on a high protein diet providing from 2.7 to 1.8 g of protein/kg of BW per day. In study two, patients were reevaluated after three weeks of a diet providing from 1.0 to 1.2 g kg‐1 of BW per day of protein. In study one (High Protein Diet), we failed to observe any rise in GFR and RPF following the protein meal (137 ± 21 basal vs. 110±14 and 472±93 basal vs. 494±93 ml/1.73 m2 of SA min‐1 at 60 min. This is in contrast with results from seven age matched controls consuming a free diet, which showed a significant rise in both GFR and RPF. In study two (low protein diet), basal GFR was significantly reduced. However after the protein load, both GFR (92±11 vs. 126±18 ml/1.73 m2 of SA min‐1) and RPF (467±83 vs. 705±102 ml/1±73 m2 min‐1) rose significantly (P |
| Databáze: | OpenAIRE |
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