Fast-Acting Black-Phosphorus-Assisted Depression Therapy with Low Toxicity

Autor:	Shuhua Wang, Kang Qin, Haoxin Cheng, Xiaolei Wang, Luojia Wu, Hongbo Xin, Liguo Jin, Wenhua Zhang, Bing-Xing Pan, Ping Hu, Yinyin Wang
Rok vydání:	2019
Předmět:	Drug Materials science media_common.quotation_subject 02 engineering and technology Pharmacology 010402 general chemistry 01 natural sciences Black phosphorus Mice Fluoxetine medicine Animals General Materials Science Depression (differential diagnoses) media_common Drug Carriers Near infrared light Low toxicity Behavior Animal Depression Mechanical Engineering virus diseases Phosphorus 021001 nanoscience & nanotechnology respiratory tract diseases 0104 chemical sciences Electrophysiological Phenomena Kinetics Mechanics of Materials 0210 nano-technology medicine.drug
Zdroj:	Advanced materials (Deerfield Beach, Fla.). 32(2)
ISSN:	1521-4095
Popis:	A black phosphorus (BP)-nanosheet-based drug-delivery system containing a therapeutic drug (Fluoxetine, Flu) is synthesized. According to subsequent behavioral, biochemical, and electrophysiological analysis, BP-Flu, after irradiated with near-infrared light (808 nm), can significantly reduce the therapy time of depression. Meanwhile, the inherent biotoxicity of Flu is also alleviated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1292bdcd5e5bbbf2177865d53674b3d1 https://pubmed.ncbi.nlm.nih.gov/31777995 Zobrazit plný text záznamu Plný text