APPLICATIONS AND LIMITATIONS OF VITREORETINAL BIOPSY TECHNIQUES IN INTRAOCULAR LARGE CELL LYMPHOMA
| Autor: | Thomas G. Ward, John Long, Sean F. Murphy, Mark S. Blumenkranz, George A. Williams, William F. Mieler |
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| Rok vydání: | 1992 |
| Předmět: |
Male
medicine.medical_specialty Fundus Oculi Biopsy medicine.medical_treatment Vitrectomy Retina medicine Humans medicine.diagnostic_test Brain Neoplasms business.industry Eye Neoplasms Large-cell lymphoma General Medicine Middle Aged medicine.disease eye diseases Vitreous Body Ophthalmology Cytopathology Female Lymphoma Large B-Cell Diffuse Radiology Tomography X-Ray Computed business Vitreous biopsy |
| Zdroj: | Retina. 12:S64-S70 |
| ISSN: | 0275-004X |
| DOI: | 10.1097/00006982-199212031-00014 |
| Popis: | The cases of 4 patients with clinical signs of intraocular large cell lymphoma are described. Initial cytopathologic examination of vitrectomy specimens failed to establish the malignant character of the vitreous infiltrates. Three of the four patients eventually developed solid central nervous system tumors, intracranial biopsy samples of which revealed large cell lymphoma, 13 months to 42 months after initial examination. In one patient, transscleral retinochoroidal biopsy confirmed the diagnosis at the same time as negative vitreous cytologic examination. Results of cytopathologic examination alone of vitreous biopsy specimens may not be sufficient to make a diagnosis in certain cases of large cell lymphoma that are subsequently documented by CNS biopsy. Careful attention should be paid to the handling, processing, and interpretation of vitrectomy specimens from patients suspected of having intraocular large cell lymphoma. Consideration should be given to immunocytologic staining and interpretation by centers that are highly experienced in vitreous cytopathology. |
| Databáze: | OpenAIRE |
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