Miliary pattern, a classic pulmonary finding of tuberculosis disease

Autor: Emilio Páez-Guillán, Alba García-Villafranca, Vanesa Alende-Castro, Cristina Macía-Rodríguez
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Microbiology (medical)
Pulmonary and Respiratory Medicine
Miliary tuberculosis
medicine.medical_specialty
Tuberculosis
TB
tuberculosis
AFB
acid-fast bacilli
medicine.medical_treatment
030106 microbiology
Population
Miliary
BAL
broncoalveolar lavage
Article
lcsh:Infectious and parasitic diseases
Mycobacterium tuberculosis
03 medical and health sciences
PCR
polymerase chain reaction
0302 clinical medicine
Internal medicine
Medicine
lcsh:RC109-216
030212 general & internal medicine
education
Ethambutol
lcsh:RC705-779
education.field_of_study
biology
TST
tuberculin skin
business.industry
Isoniazid
Immunosuppression
lcsh:Diseases of the respiratory system
Miliary pattern
medicine.disease
biology.organism_classification
IGRA
interferon-gamma release assay
CT
computed tomography
HIV
human immunodeficiency virus
Infectious Diseases
business
Rifampicin
medicine.drug
Zdroj: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 20, Iss, Pp 100179-(2020)
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
ISSN: 2405-5794
Popis: Introduction The increase in age of the population and in the use of immunosuppressive treatment makes tuberculosis (TB) with hematogenous or lymphatic dissemination a current problem. Methods We collected all the patients diagnosed with tuberculosis with miliary pulmonary pattern at the Santiago de Compostela University Teaching Hospital (NW Spain) from 1 January 2006 to 31 December 2015. Results A total of 27 patients were included, 70.4% women, with a median age of 69.0 years old. A cause of immunosuppression was observed only in 51.9% of patients. The majority of the cases (65.0%) presented pulmonary affectation. The most frequently isolated species was Mycobacterium tuberculosis (88.9%). Multiresistance to first-line antituberculosis drugs was observed only in 3.7%. 92.6% of the patients received treatment with Isoniazid, Rifampicin and Pyrazinamine, associated in 48.1% of them with Ethambutol. Two patients died during admission and there were no recurrences in the 2-years follow-up. Conclusions Miliary tuberculosis remains a current pathology. Most patients do not have a known cause of immunosuppression. The response to the typical treatment is usually good.
Databáze: OpenAIRE
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