Lung cancer in patients with idiopathic pulmonary fibrosis: A retrospective multicentre study in Europe

Autor:	Theodoros Karampitsakos, Paolo Spagnolo, Nesrin Mogulkoc, Wim A. Wuyts, Sara Tomassetti, Elisabeth Bendstrup, Maria Molina‐Molina, Effrosyni D. Manali, Ömer Selim Unat, Francesco Bonella, Nicolas Kahn, Lykourgos Kolilekas, Elisabetta Rosi, Leonardo Gori, Claudia Ravaglia, Venerino Poletti, Zoe Daniil, Thomas Skovhus Prior, Ilias C. Papanikolaou, Samantha Aso, Stavros Tryfon, Despoina Papakosta, Vasillios Tzilas, Elisabetta Balestro, Spyridon Papiris, Katerina Antoniou, Demosthenes Bouros, Athol Wells, Michael Kreuter, Argyris Tzouvelekis
Rok vydání:	2022
Předmět:	Pulmonary and Respiratory Medicine antifibrotics Lung Neoplasms Survival Databases Factual Medizin idiopathic pulmonary fibrosis monocyte count Resection survival Idiopathic Pulmonary Fibrosis surgery lung cancer Impact Humans Registries Safety Retrospective Studies
Zdroj:	Karampitsakos, T, Spagnolo, P, Mogulkoc, N, Wuyts, W A, Tomassetti, S, Bendstrup, E, Molina-Molina, M, Manali, E D, Unat, Ö S, Bonella, F, Kahn, N, Kolilekas, L, Rosi, E, Gori, L, Ravaglia, C, Poletti, V, Daniil, Z, Prior, T S, Papanikolaou, I C, Aso, S, Tryfon, S, Papakosta, D, Tzilas, V, Balestro, E, Papiris, S, Antoniou, K, Bouros, D, Wells, A, Kreuter, M & Tzouvelekis, A 2023, ' Lung cancer in patients with idiopathic pulmonary fibrosis : A retrospective multicentre study in Europe ', Respirology, vol. 28, no. 1, pp. 56-65 . https://doi.org/10.1111/resp.14363
ISSN:	1440-1843
Popis:	Background and Objective: There remains a paucity of large databases for patients with idiopathic pulmonary fibrosis (IPF) and lung cancer. We aimed to create a European registry. Methods: This was a multicentre, retrospective study across seven European countries between 1 January 2010 and 18 May 2021. Results: We identified 324 patients with lung cancer among 3178 patients with IPF (prevalence = 10.2%). By the end of the 10 year-period following IPF diagnosis, 26.6% of alive patients with IPF had been diagnosed with lung cancer. Patients with IPF and lung cancer experienced increased risk of all-cause mortality than IPF patients without lung cancer (HR: 1.51, [95% CI: 1.22–1.86], p < 0.0001). All-cause mortality was significantly lower for patients with IPF and lung cancer with a monocyte count of either
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1278951145af093d4710bbdff4fd874b https://pubmed.ncbi.nlm.nih.gov/36117239 Zobrazit plný text záznamu Plný text