Diaphragmatic dysfunction in patients with idiopathic inflammatory myopathies
| Autor: | Alexandre Demoule, Patrick Cherin, Eric Verin, Serge Herson, Michèle Levy-Soussan, Christian Straus, Thomas Similowski, Marc Zelter, Jean-Philippe Derenne, Antônio Lúcio Teixeira |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Pathology Diaphragm Neural Conduction Aspiration pneumonia Polymyositis Statistics Nonparametric Internal medicine medicine Respiratory muscle Humans Genetics (clinical) Myositis Aged Phrenic nerve business.industry Respiration Neuromuscular Diseases Middle Aged Dermatomyositis medicine.disease Respiratory Paralysis Electric Stimulation Respiratory Function Tests Diaphragm (structural system) Phrenic Nerve Neurology Pediatrics Perinatology and Child Health Cardiology Female Neurology (clinical) Inclusion body myositis business |
| Zdroj: | Neuromuscular Disorders. 15:32-39 |
| ISSN: | 0960-8966 |
| Popis: | Polymyositis, dermatopolymyositis, and inclusion body myositis imply chronic inflammation of skeletal muscles. Pulmonary complications include aspiration pneumonia, interstitial pneumonitis, or respiratory muscle myositis. This study aims at better describing their impact on respiratory muscle. Twenty-three consecutive patients (12 PM, 5 DM, 6 IBM) were studied (static inspiratory and expiratory pressures; diaphragm function in terms of the mouth and transdiaphragmatic pressure responses to bilateral phrenic stimulation). Pulmonary parenchymatous abnormalities were mild (6 cases) or absent. The mouth pressure produced by phrenic stimulation was 6.83+/-3.01 cm H2O, with 18 patients (78%) diagnosed with diaphragm weakness ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect