Alkylation of N-substituted 2-phenylacetamides
| Autor: | Milica M. Misic‐Vukovic, Slobodan D. Petrović, Dusan Z. Mijin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
alkylation under basic conditions
010405 organic chemistry Chemistry High selectivity phase-transfer conditions General Medicine General Chemistry Alkylation 010402 general chemistry 01 natural sciences 0104 chemical sciences Catalysis 2-Phenylacetamides amides lcsh:Chemistry lcsh:QD1-999 Yield (chemistry) phenylacetamides Organic chemistry alkylation under neutral conditions alkylation |
| Zdroj: | Journal of the Serbian Chemical Society, Vol 69, Iss 10, Pp 711-736 (2004) |
| ISSN: | 0352-5139 |
| Popis: | Various N-substituted phenylacetamides were alkylated using different alkylating agents under neutral and basic conditions. Reactions were performed at different reaction temperatures and in various solvents. Also, a number of various catalysts were used including phase-transfer catalysts. Reactions were followed using GC or GC-MS technique and the presence as well as the yields of the alkylation products were established. Generally, the best yield and high selectivity in the studied reactions were achieved under basic conditions where in the certain cases some products, mostly N-product were obtained solely in quantitative yields. |
| Databáze: | OpenAIRE |
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