Primary intracranial extraskeletal myxoid chondrosarcoma
| Autor: | Christophe Teriitehau, Cyrus Chargari, Olivier Jeanjean, R. Dulou, O. Goasguen, Lionel Vedrine, Arnaud Dagain |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Chemotherapy
medicine.medical_specialty business.industry Brain Neoplasms medicine.medical_treatment Intracranial Extraskeletal Myxoid Chondrosarcoma Chondrosarcoma Soft tissue Extraskeletal Myxoid Chondrosarcoma Breast Adenocarcinoma medicine.disease Myxosarcoma Surgery Frontal Lobe Radiation therapy medicine Humans Female Neurology (clinical) business Brain neoplasm Brain metastasis Aged |
| Zdroj: | Neurologia i neurochirurgia polska. 46(1) |
| ISSN: | 0028-3843 |
| Popis: | Extraskeletal myxoid chondrosarcomas (EMC) are extremely rare and are usually located in the deep soft tissues of the lower extremities. Less than 10 cases of intracranial EMC have been reported in the literature, making their management and early diagnosis difficult. We present a new case of intracranial EMC occurring in a 70-year-old woman presenting with a right frontal mass initially assumed to be a brain metastasis from breast adenocarcinoma. The optimal management of these tumours is also discussed. Analysis from the literature suggests that complete resection should be recommended, whenever feasible. Although the high risk for relapse after surgery encourages postoperative treatments, relative resistance to both radio-therapy and chemotherapy characterizes EMC. Future perspectives might include multimodal treatments with highly conformal radiotherapy modalities for dose escalation strategies or use of new molecules. Knowledge of these unusual malignant tumours will be the first step for improving patients' outcome. |
| Databáze: | OpenAIRE |
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