Light Green Crystals in May-Grünwald and Giemsa-Stained Bone Marrow Macrophages in Patients with Myeloid Leukaemia
| Autor: | Arvid Bjørneklett, Per Stavem, Bernt Ly |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty ALIZARIN RED Bone Marrow Cells Biology Stain Giemsa stain law.invention chemistry.chemical_compound Bone Marrow law hemic and lymphatic diseases medicine Humans In patient Inclusion Bodies Staining and Labeling Macrophages Hematology Leukemia Lymphoid Leukemia Myeloid Acute medicine.anatomical_structure chemistry Leukemia Myeloid Bone marrow Sudan Black B Myeloid leukaemia Electron microscope |
| Zdroj: | Scandinavian Journal of Haematology. 18:67-72 |
| ISSN: | 0036-553X |
| DOI: | 10.1111/j.1600-0609.1977.tb01479.x |
| Popis: | A patient in a terminal stage of myelomocytic leukaemia had a number of elongated crystals in many bone marrow macrophages. The crystals were up to 20 micron long, showed a characteristic light green colour with May-Grunwald & Giemsa, but did not stain with Sudan Black B or PAS. Electron microscopy showed that many of the crystals had a rhomboid form, but failed to show periodicity with the magnification used. A search was made for similar light green crystalline inclusions in patients with different types of leukaemia. Identical inclusions were found in 2 out of 5 other cases of myelomonocytic leukaemia, and in 3 out of 5 cases of chronic myeloid leukaemia. In contrast, such inclusions were not found in any of 6 patients with acute lymphoblastic leukaemia, nor in 4 patients with chronic lymphocytic leukaemia. |
| Databáze: | OpenAIRE |
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