Is glue embolization safe and effective for gastrointestinal bleeding?

Autor: Mika Kodani, Akira Adachi, Kazumichi Tsukamoto, Masayuki Endo, Shinya Fujii, Jun Makishima, Yasufumi Ohuchi, Kensuke Matsumoto, Shohei Takasugi, Shinsaku Yata
Rok vydání: 2018
Předmět:
Zdroj: Gastrointestinal Intervention, Vol 7, Iss 3, Pp 158-161 (2018)
ISSN: 2636-0012
2636-0004
DOI: 10.18528/gii180030
Popis: Transcatheter arterial embolization using N-butyl-2-cyanoacrylate (NBCA) for gastrointestinal arterial bleeding enables higher cessation rate and lower recurrent bleeding rate compared with conventional embolic materials including gelatin sponge, metallic coil, and polyvinyl alcohol (PVA) particle. Glue embolization is particularly effective in patients with coagulopathy. Even in the lower gastrointestinal tract, ischemic bowel complications by glue embolization are comparable to other agents. Glue embolization is also effective for arterial esophageal bleeding without any serious ischemic complications although the anatomy of the esophageal artery is complex and varied. For bleeding after abdominal surgery such as pancreaticoduodenectomy or hepatic lobectomy, interventional radiologists should be careful with indicating glue embolization because the presence of fewer collateral vessels can easily result in serious ischemic complications. Modified glue such as Glubran 2 (NBCA associated with methacryloxyfulfolane) can reduce the risk of ischemic complication due to its less thermal reaction, but the outcomes seem unsatisfactory.
Databáze: OpenAIRE