Pulmonary hemorrhage in hamsters after exposure to proteolytic enzymes of Bacillus subtilis
| Autor: | Leonard Greenburg, I. M. Ratner, I. P. Goldring |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Lung Diseases
Male Time Factors Intratracheal instillation Detergents Pulmonary disease Hemorrhage Bacillus subtilis Microbiology Drug Hypersensitivity Cricetinae medicine Respiratory Hypersensitivity Animals Respiratory system Adverse effect Multidisciplinary biology Proteolytic enzymes biology.organism_classification medicine.disease Enzyme assay Occupational Diseases Immunology biology.protein Female Pulmonary hemorrhage Peptide Hydrolases |
| Zdroj: | Science (New York, N.Y.). 170(3953) |
| ISSN: | 0036-8075 |
| Popis: | Single exposures of Syrian hamsters by aerosol inhalation or intratracheal instillation to proteolytic enzymes of Bacillus subtilis produced massive pulmonary hemorrhage within the first week. Of 46 animals exposed, eight died as a result of extensive hemorrhage. The remainder made uneventful recovery with no apparent residual pulmonary disease 6 weeks after exposure. |
| Databáze: | OpenAIRE |
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