Comment on 'Effects of long-term angiotensin II AT-1 receptor blockade on survival, hemodynamics and cardiac remodeling in chronic heart failure in rats'
| Autor: | R Willenheimer |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Physiology Hemodynamics Tetrazoles urologic and male genital diseases Placebo Angiotensin Receptor Antagonists Irbesartan Physiology (medical) Internal medicine medicine Animals Antihypertensive Agents Heart Failure Angiotensin II receptor type 1 urogenital system business.industry Angiotensin II Biphenyl Compounds medicine.disease female genital diseases and pregnancy complications Rats Receptor blockade Cardiac hypertrophy Heart failure Chronic Disease Cardiology Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Cardiovascular research. 43(2) |
| ISSN: | 0008-6363 |
| Popis: | I read with great interest the paper by Richer et al. [1], regarding the long-term effects of the angiotensin II AT1 receptor blocker irbesartan on survival, hemodynamics and cardiac remodelling in rats with chronic heart failure. It was shown that irbesartan 50 mg/kg/day had a major impact on survival compared to placebo in rats with heart failure following coronary ligation. The authors state that irbesartan opposed cardiac hypertrophy without … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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